Found 9 matching trials
Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations PHASE1 This study is designed to evaluate multiple clinical hypotheses and mechani...
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Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma PHASE1 This is a single institution, open-label, multi-arm, pilot study assessing ...
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Washington University School of Medicine
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In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors PHASE1 This phase I trial evaluates the safety and effectiveness of in situ immuno...
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Active Not Recruiting
Location
Los Angeles General Medical Center
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DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma PHASE1 The primary objective of the trial is the safety and tolerability of admini...
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Sidney Kimmel Comprehensive Cancer Center
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In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol® PHASE2 The purpose of this study is to evaluate the safety of sequential intratumo...
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Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer PHASE1 Both metastatic squamous non-small cell lung cancer (NSCLC) and extensive s...
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Multiple Locations
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Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer PHASE1 This Phase 1 study will evaluate safety and the immune response to pooled m...
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Sidney Kimmel Comprehensive Cancer Center
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A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma PHASE1 This is a study to determine the clinical benefit (how well the drug works)...
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California Pacific Medical Center Research Institute
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Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant PHASE1 This phase I trial tests peptide-pulsed dendritic cell vaccination in combi...
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UCLA / Jonsson Comprehensive Cancer Center
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